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Tuesday, July 6, 2010

The complex world of protein interactions

Many cellular functions rely on interactions between different proteins. Until recently, it had been thought that these interactions were relatively simple, with each type of intracellular communication involving no more than a few different proteins. A team of scientists from the Universities of Edinburgh, Michigan, Toronto have shown how wrong that is.

They examined hundreds of yeast proteins and found thousands of connections between them. Many of the proteins were linked in complex webs. Among other implications, this means that drugs might be made much more affective by targeting them to protein networks rather than particular proteins.